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SML0138

Sigma-Aldrich

Levalbuterol hydrochloride

≥98% (HPLC)

Synonym(s):

(R)-salbutamol hydrochloride, Levosalbutamol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C13H21NO3 · HCl
CAS Number:
50293-90-8
Molecular Weight:
275.77
MDL number:
MFCD08067728
UNSPSC Code:
12352200
PubChem Substance ID:
329825186
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -25 to -35°, c = 0.1 in H2O

storage condition

desiccated

color

white to tan

solubility

H2O: ≥15 mg/mL

storage temp.

2-8°C

SMILES string

Cl.CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1

InChI

1S/C13H21NO3.ClH/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;/h4-6,12,14-17H,7-8H2,1-3H3;1H/t12-;/m0./s1

InChI key

OWNWYCOLFIFTLK-YDALLXLXSA-N

Gene Information

human ... ADRB2(154)

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Application

Levalbuterol hydrochloride may be used in β2-adrenergic-mediated cell signaling studies.

Biochem/physiol Actions

Levalbuterol (levosalbutamol) is the more active isomer of albuterol. Levalbuterol is a β-adrenergic agonist; a bronchodilator used clinically to treat asthma and COPD..
Levalbuterol is (R)-albuterol that exhibits bronchodilator effect and is more effective than racemic albuterol for the treatment of exacerbation of asthma in pediatric populations.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Madhu D Hardasmalani et al.
Pediatric emergency care, 21(7), 415-419 (2005-07-20)
To compare levalbuterol and racemic albuterol for the treatment of acute exacerbation of asthma in pediatric population. Prospective, double-blind, randomized research trial in a pediatric emergency department of an urban tertiary care hospital. Children 5 to 21 years with a

Articles

β-Adrenoceptors

β-Adrenoceptors are activated either by norepinephrine or epinephrine. Learn more about the role of β-adrenoceptors in protein expression, cell signaling, and metabolism research.

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