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SML0275

Sigma-Aldrich

rac BHFF

≥98% (HPLC)

Synonym(s):

5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl) -2(3H)-benzofuranone, 5,7-Di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one

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About This Item

Empirical Formula (Hill Notation):
C17H21F3O3
CAS Number:
Molecular Weight:
330.34
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: ≥15 mg/mL

storage temp.

2-8°C

SMILES string

CC(C)(C)c1cc(c2OC(=O)C(O)(c2c1)C(F)(F)F)C(C)(C)C

InChI

1S/C17H21F3O3/c1-14(2,3)9-7-10(15(4,5)6)12-11(8-9)16(22,13(21)23-12)17(18,19)20/h7-8,22H,1-6H3

InChI key

RVNOANDLZIIFHB-UHFFFAOYSA-N

Biochem/physiol Actions

rac BHFF is an orally active, potent and selective positive allosteric modulator of GABA-B. rac BHFF increases the potency and efficacy of GABA.

Features and Benefits

This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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