Skip to Content
MilliporeSigma
All Photos(1)

Documents

SML0418

Sigma-Aldrich

ML-161

≥98% (HPLC)

Synonym(s):

2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]-benzamide

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C17H17BrN2O2
CAS Number:
Molecular Weight:
361.23
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL (clear solution)

storage temp.

2-8°C

SMILES string

CCCC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1

InChI

1S/C17H17BrN2O2/c1-2-6-16(21)19-12-7-5-8-13(11-12)20-17(22)14-9-3-4-10-15(14)18/h3-5,7-11H,2,6H2,1H3,(H,19,21)(H,20,22)

InChI key

DFOVLSMXPWPCFH-UHFFFAOYSA-N

Biochem/physiol Actions

ML-161 is an antagonist of the protease-activated receptor 1 (PAR1), that inhibits thrombin and SFLLN-induced platelet activation. ML-161 dose dependently inhibits SFLLN-induced expression of P-selectin with an IC50 of 0.26 μM.

pictograms

Environment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

The search for a functional thrombin receptor, using expression cloning methods, led to the discovery of a G protein-coupled receptor that mediates the actions of thrombin on platelets and endothelial cells.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service