SML0629
Mitochondrial Fusion Promoter M1
≥95% (HPLC)
Synonym(s):
(E)-4-Chloro-2-(1-(2-(2,4,6-trichlorophenyl)hydrazono)ethyl)phenol, 1-(5-Chloro-2-hydroxyphenyl)-ethanone 2-(2,4,6-trichlorophenyl)hydrazone
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About This Item
Empirical Formula (Hill Notation):
C14H10Cl4N2O
CAS Number:
Molecular Weight:
364.05
UNSPSC Code:
12352200
NACRES:
NA.77
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Quality Level
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
Application
Mitochondrial Fusion Promoter M1 has been used as a fusion promoter:
- to study its effects on peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α expression in breast cancer cells
- to study the link between nucleoside diphosphate kinase 3 (NME3)-regulated mitochondrial fluctuations and stability of genome in NME3 knockdown cells
- to study its effects on mitochondrial fusion in neuronal cells
Biochem/physiol Actions
Mitochondrial Fusion Promoter M1 is a cell permeable hydrazone that enhances mitochondrial fusion. M1 protects cells from mitochondrial fragmentation associated cell death. Mitochondrial Fusion Promoter M1 does not interfere with endoplasmic reticula (ER) and lysosomes morphology.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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