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SML1172

Sigma-Aldrich

FFN102

≥98% (HPLC)

Synonym(s):

4-(2-Amino-ethyl)-6-chloro-7-hydroxy-chromen-2-one trifluoroacetate, 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one trifluoroacetate, Mini 102, Mini102

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About This Item

Empirical Formula (Hill Notation):
C11H10ClNO3 · CF3CO2H
CAS Number:
1234064-11-9
Molecular Weight:
353.68
UNSPSC Code:
12352200
PubChem Substance ID:
329825700
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to light brown

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

FC(F)(F)C(O)=O.NCCC(C1=CC(Cl)=C(O)C=C1O2)=CC2=O

InChI

1S/C11H10ClNO3.C2HF3O2/c12-8-4-7-6(1-2-13)3-11(15)16-10(7)5-9(8)14;3-2(4,5)1(6)7/h3-5,14H,1-2,13H2;(H,6,7)

InChI key

OGHPXKAKVMJGQH-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

FFN102 is a pH-responsive fluorescent false neurotransmitter that acts as a dopamine transporter substrate (DAT) and also a substrate for vesicular monoamine transporter 2 (VMAT2). FFN102 selectively labels dopamine cell bodies and dendrites in ventral midbrain and dopaminergic synaptic terminals in dorsal striatum. Its greater fluorescence emission in neutral than acidic environments allows the visualization of dopamine release at individual presynaptic terminals and in situ pH measurement of catecholamine secretory vesicles.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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