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SML1335

Sigma-Aldrich

Pidotimod

≥98% (HPLC)

Synonym(s):

(4R)-3-(5-Oxo-L-prolyl)-1,3-thiazolidine-4-carboxylic acid, (R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid, (R)-3-[(S)-(5-Oxo-2-pyrrolidinyl) carbonyl]-thiazolidine-4-carboxylic acid, 3-L-Pyroglutamyl-L-thiaziolidine-4carboxylic acid, PGT/1A

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About This Item

Empirical Formula (Hill Notation):
C9H12N2O4S
CAS Number:
121808-62-6
Molecular Weight:
244.27
MDL number:
MFCD00867583
UNSPSC Code:
12352200
PubChem Substance ID:
329825793
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D -135 to -155°, c = 1 in 6 M HCl

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

room temp

SMILES string

OC([C@@H]1CSCN1C([C@H]2NC(CC2)=O)=O)=O

InChI

1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1

InChI key

UUTKICFRNVKFRG-WDSKDSINSA-N

Biochem/physiol Actions

Pidotimod is a dipeptide immunostimulant with biological activity on both the adaptive and the innate immune responses. Pidotimod has been reported to modulate airway epithelial cells functions involved in host-virus interaction possibly through NF-kB activation, promote functional maturation of dendritic cells, and facilitate M2 macrophage polarization and function. Pidotimod has been investigated for use to increase response to recurrent respiratory infections primarily in children.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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