SML2906
ERGi-USU
≥98% (HPLC)
Synonym(s):
1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol, 1-[2-Thiazolylazo]-2-naphthol, NSC139021, TAN
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About This Item
Empirical Formula (Hill Notation):
C13H9N3OS
CAS Number:
Molecular Weight:
255.30
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
powder
color
faint brown to dark red
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
InChI
1S/C13H9N3OS/c17-11-6-5-9-3-1-2-4-10(9)12(11)15-16-13-14-7-8-18-13/h1-8,17H
InChI key
IOMXCGDXEUDZAK-UHFFFAOYSA-N
Biochem/physiol Actions
ERGi-USU is a selective and potent inhibitor of growth of ERG positive cancer cell lines, while spearing normal prostate or endothelial cells. It potently inhibits growth of ERG positive VCaP xenografts in mice. ERGi-USU is a potent and selective ligand of the ribosomal atypical kinase RIOK2 (right open reading frame (RIO) kinase 2) that induces ribosomal stress.
wgk_germany
WGK 3
Certificates of Analysis (COA)
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