SML3091
Irresistin-16
≥98% (HPLC)
Synonym(s):
7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine,7-([1,1?-biphenyl]-4-ylmethyl), IRS-16
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C23H19N5
CAS Number:
Molecular Weight:
365.43
UNSPSC Code:
51111800
NACRES:
NA.77
Recommended Products
![tert-Butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/233/713/93c04eb9-4177-4838-ad16-4fd78d5be69c/640/93c04eb9-4177-4838-ad16-4fd78d5be69c.png)
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
NC1=NC(N)=NC2=C1C3=C(C=C2)N(CC4=CC=C(C=C4)C5=CC=CC=C5)C=C3
Biochem/physiol Actions
Irresistin-16, an SCH 79797 derivative, is a broad spectrum bactericidal antibiotic that is effective in both gram-positive and gram-negative bacteria and exhibits low frequency of resistance. Irresistin-16 act through interruption of bacterial folate metabolism and bacterial membrane integrity. It inhibits E. coli dihydrofolate reductase FolA. Irresistin-16 is effective in mouse gonorrhea infection model.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
James K Martin et al.
Cell, 181(7), 1518-1532 (2020-06-05)
The rise of antibiotic resistance and declining discovery of new antibiotics has created a global health crisis. Of particular concern, no new antibiotic classes have been approved for treating Gram-negative pathogens in decades. Here, we characterize a compound, SCH-79797, that
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service