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SML3301

Sigma-Aldrich

cisVZ185

≥98% (HPLC)

Synonym(s):

(2S,4S)-N-(2-(5-(4-(2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)piperazin-1-yl)pentyloxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide, Cis-VZ 185, Cis-VZ-185, Cis-VZ185, VZ 185 inactive control, VZ 185 negative control, VZ-185 inactive control, VZ185 inactive control, VZ185 negative control

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About This Item

Empirical Formula (Hill Notation):
C53H67FN8O8S
CAS Number:
Molecular Weight:
995.21
UNSPSC Code:
51111800
NACRES:
NA.32

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=C(NCC1=C(OCCCCCN2CCN(CC3=C(OC)C=C(C(C4=C5C=NC=C4)=CN(C)C5=O)C=C3OC)CC2)C=C(C=C1)C6=C(C)N=CS6)[C@H]7N(C([C@@H](NC(C8(F)CC8)=O)C(C)(C)C)=O)C[C@@H](O)C7

Biochem/physiol Actions

cisVZ185 is the inactive cis-isomer of and the recommended negative control for the potent and selective dual BRD7 and BRD9 degrader VZ185.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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