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SML3432

Sigma-Aldrich

Brevianamide F

≥98% (HPLC)

Synonym(s):

(3S,8aS)-hexahydro-3-(1H-indol-3-ylmethyl)-pyrrolo[1,2-a]pyrazine-1,4-dione, cyclo-(L-Trp-L-Pro), cyclo-(tryptophanyl-prolyl)

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About This Item

Empirical Formula (Hill Notation):
C16H17N3O2
CAS Number:
Molecular Weight:
283.33
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

InChI

1S/C16H17N3O2/c20-15-14-6-3-7-19(14)16(21)13(18-15)8-10-9-17-12-5-2-1-4-11(10)12/h1-2,4-5,9,13-14,17H,3,6-8H2,(H,18,20)/t13-,14-/m0/s1

InChI key

RYFZBPVMVYTEKZ-KBPBESRZSA-N

Biochem/physiol Actions

Brevianamide F is a naturally occurring cyclic dipeptide diketopiperazine (DKP) with antibacterial activity. It has shown activity against M. luteus and against methicillin-sensitive and resistant S. aureus among others.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Pei Huang et al.
Applied microbiology and biotechnology, 100(17), 7437-7447 (2016-03-16)
Microbes belonging to the genus Verrucosispora possess significant chemical diversity and biological properties. They have attracted the interests of many researchers and are becoming promising resources in the marine natural product research field. A bioassay-guided isolation from the crude extract

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