Skip to Content
MilliporeSigma
All Photos(2)

Documents

SML3753

Sigma-Aldrich

TH301

≥98% (HPLC)

Synonym(s):

1-​(4-​Chlorophenyl)​-​N-​[2,​6-​dihydro-​2-​(4-​methoxyphenyl)​-​5,​5-​dioxido-​4H-​thieno[3,​4-​c]​pyrazol-​3-​yl]​-cyclopentanecarboxam​ide

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C24H24ClN3O4S
CAS Number:
450338-32-6
Molecular Weight:
485.98
UNSPSC Code:
12352200
NACRES:
NA.21

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(C1(CCCC1)C2=CC=C(Cl)C=C2)NC3=C(CS(C4)(=O)=O)C4=NN3C5=CC=C(OC)C=C5

Biochem/physiol Actions

TH301 is a circadian clock modulator that lengthens a circadian period in cells and tissues. It selectively stabilizes CRY2 through interaction with FAD-binding pocket. TH301 strongly enhanced brown adipocyte differentiation in culture. TH301 showed no or only minor effects on CKIδ, CKIα and CK2 activities in vitro.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service