SRP0454
BRD2, BD1, BD2 (65-459) GST tag human
recombinant, expressed in E. coli, ≥80% (SDS-PAGE)
Synonym(s):
FSH, NAT, RING3, RNF3, bromodomain containing 2
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
biological source
human
recombinant
expressed in E. coli
assay
≥80% (SDS-PAGE)
form
aqueous solution
mol wt
71.1 kDa
packaging
pkg of 100 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... BRD2(6046)
General description
Human Bromodomain containing 2, also known as BRD2, RING3 or RNF3 (GenBank Accession No. NM_005104) amino-acids 65 – 459 with N-terminal GST-tag, MW = 71.1 kDa, expressed in an E. coli expression system.
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Takashi Umehara et al.
FEBS letters, 584(18), 3901-3908 (2010-08-17)
The BET family proteins recognize acetylated chromatin through their two bromodomains, acting as transcriptional activators or tethering viral genomes to the mitotic chromosomes of their host. The structural mechanism for how the N-terminal bromodomain of human BRD2 (BRD2-BD1) deciphers the
Enyuan Shang et al.
Journal of cellular biochemistry, 112(10), 2784-2793 (2011-05-25)
The human BRD2 gene has been linked and associated with a form of common epilepsy and electroencephalographic abnormalities. Disruption of Brd2 in the mouse revealed that it is essential for embryonic neural development and that viable Brd2(+/-) heterozygotes show both
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