SRP5264
KAT2A (GCN5), active, GST tagged human
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonym(s):
GCN5, GCN5L2, HsGCN5, MGC102791, PCAF-b, hGCN5
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About This Item
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biological source
human
recombinant
expressed in baculovirus infected Sf9 cells
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
17.6-26.4 nmol/min·mg
mol wt
~82 kDa
NCBI accession no.
application(s)
cell analysis
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KAT2A(2648)
General description
KAT2A (K (lysine) acetyltransferase 2A) is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator which functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner. KAT2A control chromosome stability by coordinating the ATR checkpoint and double-strand break processing with autophagy. KAT2A acetyltransferases have homologous sequences and enzymatic activities which are important for recognition of nucleosomal substrates.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Preparation Note
After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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