SRP8059
Jagged-2 (human): FC (human)
recombinant, expressed in HEK 293 cells, ≥90% (SDS-PAGE)
Synonym(s):
Alpha-ketoglutarate-dependent dioxygenase FTO, Protein jagged-2, hJ2
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
recombinant
expressed in HEK 293 cells
assay
≥90% (SDS-PAGE)
form
lyophilized
mol wt
~150 kDa by SDS-PAGE
impurities
<0.1 EU/μgtested
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... JAG2(3714)
General description
Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.
Sequence
Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.
Physical form
Lyophilized. Contains PBS + 0.02 % CHAPS.
Reconstitution
Reconstitute with 100μl sterile water.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service