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T0175

Sigma-Aldrich

Troponin T from human heart

≥60% (SDS-PAGE), lyophilized powder

Synonym(s):

Tn-T

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human heart

Quality Level

form

lyophilized powder

purified by

affinity chromatography

concentration

≥60% (SDS-PAGE)

technique(s)

ELISA: suitable

solubility

10 mM HCl: 500 μg/mL, clear, colorless

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... TNNT2(7139)

General description

The cardiac troponin T gene (TNNT2) is located on human chromosome 1 and spans around 17kb. It codes for a 288-amino-acid peptide of 36−39kDa.

Application

Troponin T from human heart has been used in competitive enzyme-linked immunosorbent assay (ELISA) for the quantification of troponin T (TnT).

Biochem/physiol Actions

The tropomyosin-binding subunit of troponin. The cardiac troponin T gene (TNNT2) helps to connect the troponin complex to α-tropomyosin, thereby participates in the modulation of contractile function.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Inherited cardiomyopathies
Emery and Rimoin's Principles and Practice of Medical Genetics, 1-38 (2013)
A skeletal muscle troponin T specific ELISA based on the use of an antibody against the soluble troponin T (16-31) fragment
Tsitsilonis O E, et al.
Journal of Immunological Methods, 268(2), 141-148 (2002)

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