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T1502

Sigma-Aldrich

Triethanolamine hydrochloride

≥99.5% (titration)

Synonym(s):

2,2′,2′′-Nitrilotriethanol hydrochloride, Tris(2-hydroxyethyl)amine hydrochloride

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About This Item

Linear Formula:
(HOCH2CH2)3N · HCl
CAS Number:
637-39-8
Molecular Weight:
185.65
Beilstein/REAXYS Number:
3909940
EC Number:
211-284-2
MDL number:
MFCD00012596
UNSPSC Code:
12161700
PubChem Substance ID:
24899972
NACRES:
NA.25

Quality Level

200

assay

≥99.5% (titration)

form

crystalline powder

useful pH range

7.3-8.3

pKa (25 °C)

7.8

mp

177-179 °C (lit.)

solubility

water: 0.333 g/mL, clear, colorless

application(s)

diagnostic assay manufacturing

SMILES string

Cl.OCCN(CCO)CCO

InChI

1S/C6H15NO3.ClH/c8-4-1-7(2-5-9)3-6-10;/h8-10H,1-6H2;1H

InChI key

HHLJUSLZGFYWKW-UHFFFAOYSA-N

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General description

Triethanolamine (TEA) belongs to the family of ethanolamine. It includes the properties of both amines and alcohols. Addition of TEA to an acidic buffer facilitates the determination of fluoride in inorganic orthophosphates by using a fluoride-selective electrode.

Application

Triethanolamine hydrochloride has been used:
  • in the preparation of triethanolamine buffer
  • in rinsing the digested sections, prepared for in situ hybridization
  • as a component of solution A to prepare TA-complement haemolysis buffer (TA-CHB)

Biochem/physiol Actions

Triethanolamine hydrochloride acts as a surfactant or pH adjuster. It is also used as an emulsifier in cosmetics and several topical medications.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Safety assessment of triethanolamine and triethanolamine-containing ingredients as used in cosmetics
Fiume M, et al.
International Journal of Toxicology, 32(3\_suppl), 59S-83S (2013)
The serum complement system: a simplified laboratory exercise to measure the activity of an important component of the immune system
Inglis JE, et al.
Advances in Physiology Education, 32(4), 317-321 (2008)
allergic Contact Dermatitis to Triethanolamine in a Child
Milanesi N, et al.
Pediatric Dermatology, 32(3), e112-e113 (2015)
Gender difference in hypothalamic-pituitary-adrenal axis response to alcohol in the rat: activational role of gonadal steroids
Ogilvie KM and Rivier C
Brain Research, 766(1-2), 19-28 (1997)
Optimal conditions for the kinetic assay of serum glutamate dehydrogenase activity at 37? C
Ellis G and Goldberg DM
Clinical Chemistry, 18(6), 523-527 (1972)
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