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U6375

Sigma-Aldrich

Uridine 5′-monophosphate disodium salt

≥99%

Synonym(s):

5′-UMP-Na2, U 5′-P, UMP, Uridylic acid disodium salt

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About This Item

Empirical Formula (Hill Notation):
C9H11N2Na2O9P
CAS Number:
3387-36-8
Molecular Weight:
368.15
Beilstein/REAXYS Number:
3582885
EC Number:
222-211-9
MDL number:
MFCD00006525
UNSPSC Code:
12352204
PubChem Substance ID:
24900433
NACRES:
NA.26

biological source

(chemical)

Quality Level

200

assay

≥99%

form

powder

storage temp.

−20°C

SMILES string

[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H13N2O9P.2Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

InChI key

KURVIXMFFSNONZ-WFIJOQBCSA-L

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General description

Uridine 5′-monophosphate is a pyrimidine mononucleotide. It is formed by decarboxylation of orotidine 5′-monophosphate. UMP is further converted to UTP (uridine 5′-triphosphate) using kinases.

Application

Uridine 5′-monophosphate disodium salt has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucleotides on growth of specific intestinal bacteria.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism.
Poirier S, et al.
The Journal of Biological Chemistry, 289, 18736-18751 (2014)
Nucleotides modify growth of selected intestinal bacteria in vitro.
Sauer N, et al.
Livestock Science, 133, 161-163 (2010)
Adams RLP, et al.
The Biochemistry of the Nucleic Acids (2013)
Stefanie Bäurer et al.
Journal of chromatography. A, 1560, 45-54 (2018-05-24)
Herein, we present a novel silica-based stationary phase modified with N-propyl-N'-2-pyridylurea selector. Due to the weakly basic properties of the pyridine selector and the presence of residual silanols after selector immobilization, a zwitterionic surface with a pI observed at approximately
Charlotte Vinther Schmidt et al.
Scientific reports, 10(1), 20077-20077 (2020-11-20)
Food and flavour pairing are commonly used as an empirically based phenomenology by chefs and food innovators for creating delicious dishes. However, there is little if any science behind the pairing systems used, and it appears that pairing is determined
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