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47783

Supelco

(±)-α-Tocopherol

analytical standard

Synonym(s):

DL-all-rac-α-Tocopherol, Vitamin E

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About This Item

Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
Molecular Weight:
430.71
Beilstein/REAXYS Number:
94012
EC Number:
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:
E Number:
E307

grade

analytical standard

Quality Level

form

liquid

CofA

current certificate can be downloaded

feature

standard type fat soluble vitamin

packaging

ampule of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

density

0.950 g/mL at 20 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

-10 to -25°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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General description

α-Tocopherol is a form of fat-soluble vitamin E and shows anti-oxidant, anti-inflammatory, anti-cell proliferative, and anti-cancer properties.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

The analytical standard can also be used as follows:

  • Simultaneous determination of vitamin A and all four tocopherol isomers in human serum samples by ultra-high performance liquid chromatography (UHPLC) combined with fluorescence detection following their liquid-liquid extraction (LLE)
  • Multi-residue analysis of vitamin B (B1, B2, B5, and B9), and vitamin E (α-tocopherol, β-tocopherol, α-tocotrienol, and β-tocotrienol) in grass and grain samples of four different wheat varieties by liquid chromatography-electrospray ionization/multistage mass spectrometry (LC-ESI-MS/MS)
  • Separation and estimation of four tocopherols and four tocotrienols in pecan nut cultivar samples using non-aqueous reversed-phase high-performance liquid chromatography (NARP-HPLC) coupled with atmospheric pressure chemical ionization-tandem mass spectrometric (APCI-MS/MS) detection
  • Analysis of different cold pressed oil samples to detect and quantify eight tocol- homologs using a chemometrically-assisted optimized high-performance liquid chromatography (HPLC) with fluorescence detection (FLD) based method
  • Multi-residue determination of tocopherols in aromatic peanut oil (APO) and four refined vegetable oils using high-performance liquid chromatography with UV detection to detect adulteration

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

wgk_germany

WGK 1

flash_point_f

closed cup

flash_point_c

closed cup

ppe

Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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DL-α-Tocopherol acetate certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

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Simultaneous determination of retinol, ?-tocopherol and ?-carotene in serum by isocratic high-performance liquid chromatography
Arnaud.J, et al.
Journal of Chromatography. B, Biomedical Applications, 572(1-2), 103-116 (1991)
Simultaneous determination of plasma retinol, alpha-tocopherol, lycopene, alpha-carotene, and beta-carotene by high-performance liquid chromatography.
Miller WK, et al.
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Protocols

Separation of (±)-α-Tocopherol, analytical standard; Menadione (K3), analytical standard; (+)-γ-Tocopherol, analytical standard; Cholecalciferol (D3), analytical standard

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

Separation of Retinyl acetate, analytical standard; δ-Tocopherol, analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Retinol palmitate, analytical standard.

Separation of Retinyl acetate, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; δ-Tocopherol, analytical standard; Retinol palmitate, analytical standard

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