Skip to Content
MilliporeSigma
All Photos(1)

Documents

50165-U

Nucleosil® C18 HPLC Column

5 μm particle size, L × I.D. 12.5 cm × 4 mm

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

agency

suitable for USP L1

Quality Level

product line

Nucleosil®

feature

endcapped

manufacturer/tradename

Nucleosil®

extent of labeling

15% Carbon loading

parameter

≤70 °C temp. range
400 bar pressure (5801 psi)

technique(s)

HPLC: suitable

L × I.D.

12.5 cm × 4 mm

surface area

350 m2/g

matrix

octadecyl

matrix active group

C18 (octadecyl) phase

particle size

5 μm

pore size

100 Å

separation technique

reversed phase

Looking for similar products? Visit Product Comparison Guide

Application


  • Quantification and Validation of Stability-Indicating RP-HPLC Method for Efavirenz: Demonstrates the utility of Nucleosil® C18 HPLC Column in pharmaceutical analysis, particularly in quality control and stability testing of Efavirenz, ensuring compliance with regulatory standards (Gurumukhi VC, Bari SB, 2022).

  • Development of new method for simultaneous analysis of piracetam and levetiracetam: This study uses the Nucleosil® C18 column to develop robust methods for analyzing neurological medications in pharmaceuticals and biological fluids, contributing to drug stability studies (Siddiqui FA et al., 2014).

  • HPLC method for determination of biologically active epoxy-transformers of treosulfan: The column′s application in plasma analysis highlights its role in pharmacokinetic studies, offering precise measurements critical for dosing and therapeutic monitoring (Główka FK et al., 2012).

  • HPLC analysis of mitoxantrone in mouse plasma and tissues: Illustrates the column′s effectiveness in a pharmacokinetic study, underscoring its importance in the preclinical evaluation of cancer therapies (An G, Morris ME, 2010).

  • Development and validation of an HPLC method for vancomycin: This application in a pharmacokinetic study highlights the column′s critical role in the development and validation of methods for antibiotic analysis, ensuring therapeutic efficacy and safety (Jesús Valle MJ et al., 2008).

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Nucleosil is a registered trademark of Macherey-Nagel GmbH & Co. KG

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service