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52638-U

Supelco

Discovery® DSC-NH2 SPE Tube

bed wt. 500 mg, volume 6 mL, pk of 30

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About This Item

UNSPSC Code:
41115712
NACRES:
NB.21

material

PE frit (20 μm)
polypropylene

Quality Level

feature

endcapped

composition

bed wt., 500 mg

packaging

pk of 30

technique(s)

solid phase extraction (SPE): suitable

surface area

480 m2/g

volume

6 mL

matrix

silica gel base material (irregularly shaped, acid washed)

matrix active group

amino phase

particle size

50 μm

pore size

70 Å pore size

pKa 

9.8

capacity

~0.43 meq/g capacity

application(s)

food and beverages

separation technique

ion exchange
normal phase

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General description

Retention Mechanism: Normal phase or Anion-exchange
Sample Matrix Compatibility: Organic or aqueous solutions

  • Polymerically bonded, aminopropyl phase that is very polar in nature (hydrogen bonding) allowing for both normal phase and ion exchange applications
  • A weak anion exchanger with a pKa of 9.8. At pH 7.8 or below, the functional groups are positively charged
  • Ion exchange capacity is ∼ 0.43 meq/g.
  • Allows the rapid release of very strong anions such as sulfonic acids that may be retained irreversibly by strong anion exchangers
  • Can be used in some reversed-phase applications (due to ethyl spacer); however, it is predominately used as an ion-exchange or normal phase sorbent due to its polar nature

Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 3

flash_point_f

>464.0 °F

flash_point_c

> 240 °C


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Articles

SPE retention mechanism in this case is based on the electrostatic attraction of charged functional groups of the analyte(s) to oppositely charged functional groups on the sorbent.

Protocols

Retention occurs through polar interaction between the sorbent and analytes. Typical sample matrices that can be employed in normal-phase SPE include hydrocarbon or fatty oils diluted in a solvent like hexane, isooctane, chlorinated solvent, THF, diethyl ether, or ethyl acetate.

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