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1150706

USP

Crospovidone

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Polyvinylpyrrolidone, PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
MDL number:
MFCD00149016
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

crospovidone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Crospovidone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.
Sales restrictions may apply.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

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Sigma-Aldrich

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Atsuko Adachi et al.
Contact dermatitis, 48(3), 133-136 (2003-05-21)
A 59-year-old woman who had had several episodes of contact urticaria after hair treatment, developed anaphylaxis after vaginal application of povidone-iodine solution for disinfection. Prick tests showed wheal-and-flare responses to both povidone-iodine (0.1% aqueous) and polyvinylpyrrolidone (povidone, PVP) (0.001% aq.)
[Gordon's polyvinylpyrrolidone test].
J Aebersold
Helvetica medica acta, 32(3), 227-246 (1965-09-01)
Povidone-iodine solutions in traumatic wound preparation.
M S Oberg
The American journal of emergency medicine, 5(6), 553-555 (1987-11-01)
Polyvinylpyrrolidone (PVP), its diagnostic, therapeutic and technical application and consequences thereof.
W Wessel et al.
Arzneimittel-Forschung, 21(10), 1468-1482 (1971-10-01)
Patricia C Buchsel
Expert opinion on drug metabolism & toxicology, 4(11), 1449-1454 (2008-10-28)
Painful oral lesions in patients with cancer, HIV or aphthous ulcers can cause significant pain and discomfort. Those with oral mucositis (OM) resulting from high-dose chemotherapy or irradiation are the most at risk for painful lesions that lead to significant
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