1154004
USP
Cyclizine hydrochloride
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
1-Benzhydryl-4-methylpiperazine hydrochloride, Marezine hydrochloride
About This Item
Recommended Products
grade
pharmaceutical primary standard
API family
cyclizine
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
InChI
1S/C18H22N2.ClH/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18H,12-15H2,1H3;1H
InChI key
UKPBEPCQTDRZSE-UHFFFAOYSA-N
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General description
Application
- Apoptotic pathways in macrophages: Cyclizine hydrochloride was studied for its ability to induce cytotoxicity and apoptosis in macrophages through both extrinsic and intrinsic pathways, suggesting its potential implications in immunomodulatory therapies (Lu et al., 2024).
- Chemometric methods in impurity analysis: Advanced chemometric methods have been employed to determine cyclizine hydrochloride along with other compounds in pharmaceutical products, highlighting its importance in ensuring the purity and efficacy of drug formulations (Saad et al., 2022).
- Anti-inflammatory effects in pharmacology: Cyclizine derivatives were synthesized and evaluated for anti-inflammatory performance on Wistar rats, providing insights into the therapeutic potential of cyclizine modifications in treating inflammation (Ahmadi et al., 2012).
Analysis Note
Other Notes
related product
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
Storage Class
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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