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1379106

USP

Megestrol acetate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

17α-Acetoxy-6-methyl-4,6-pregnadiene-3,20-dione, 17α-Hydroxy-6-methyl-4,6-pregnadiene-3,20-dione 17-acetate, 17α-Hydroxy-6-methyl-6-dehydroprogesterone 17-acetate, Megestrol 17-acetate

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About This Item

Empirical Formula (Hill Notation):
C24H32O4
CAS Number:
595-33-5
Molecular Weight:
384.51
Beilstein/REAXYS Number:
1917291
MDL number:
MFCD00056470
UNSPSC Code:
41116107
PubChem Substance ID:
329750339
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

megesterol

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C

InChI

1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1

InChI key

RQZAXGRLVPAYTJ-GQFGMJRRSA-N

Gene Information

human ... PGR(5241)

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Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Megestrol acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

N1080005

Nomegestrol acetate impurity A, European Pharmacopoeia (EP) Reference Standard

Y0001594

Megestrol acetate impurity K, European Pharmacopoeia (EP) Reference Standard

Y0001514

Megestrol acetate, European Pharmacopoeia (EP) Reference Standard

Y0001507

Megestrol acetate for peak identification, European Pharmacopoeia (EP) Reference Standard

Y0001524

Megestrol acetate for system suitability, European Pharmacopoeia (EP) Reference Standard

1379128

Megestrol Acetate Related Compound C, United States Pharmacopeia (USP) Reference Standard

BP223

Megestrol acetate, British Pharmacopoeia (BP) Reference Standard

1379139

Megestrol Acetate Related Compound D, United States Pharmacopeia (USP) Reference Standard

1379172

Megesterol Acetate Related Compound H, United States Pharmacopeia (USP) Reference Standard

BP222

Megestrol, British Pharmacopoeia (BP) Reference Standard

Y0002161

Nomegestrol acetate for ID and assay CRS, CRS, European Pharmacopoeia (EP) Reference Standard

Y0002169

Nomegestrol acetate impurity B, CRS, European Pharmacopoeia (EP) Reference Standard

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

Storage Class

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yo Han Kim et al.
Clinical therapeutics, 37(2), 439-447 (2014-12-03)
Megestrol acetate oral suspension is an appetite stimulant indicated for cachexia. It is available in a conventional formulation and as a nanocrystal dispersion. The aim of this study was to compare the tolerability and pharmacokinetics of these formulations under fed
Navdha Mittal et al.
PloS one, 9(10), e110410-e110410 (2014-10-24)
Resistance to progestin treatment is a major hurdle in the treatment of advanced and reoccurring endometrial cancer. Fenretinide is a synthetic retinoid that has been evaluated in clinical trials as a cancer therapeutic and chemo-preventive agent. Fenretinide has been established

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