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  • Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1.

Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1.

Organic & biomolecular chemistry (2009-03-06)
David Foley, Patrick Bailey, Myrtani Pieri, David Meredith
PMID19262922
ABSTRACT

Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.

MATERIALS
Product Number
Brand
Product Description
N6142
Supelco
Nabumetone, analytical standard
N0020000
Nabumetone, European Pharmacopoeia (EP) Reference Standard