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117455

Sigma-Aldrich

p-Toluenesulfonyl fluoride

98%

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About This Item

Linear Formula:
CH3C6H4SO2F
CAS Number:
455-16-3
Molecular Weight:
174.19
EC Number:
207-238-6
MDL number:
MFCD00007421
UNSPSC Code:
12352100
PubChem Substance ID:
24847330
NACRES:
NA.22

Quality Level

100

assay

98%

form

solid

reaction suitability

reaction type: click chemistry

bp

112 °C/16 mmHg (lit.)

mp

41-42 °C (lit.)

SMILES string

Cc1ccc(cc1)S(F)(=O)=O

InChI

1S/C7H7FO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3

InChI key

IZZYABADQVQHLC-UHFFFAOYSA-N

Related Categories

General description

p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease.

Application

p-Toluenesulfonyl fluoride was used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.
Protease inhibitor.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

222.8 °F - closed cup

flash_point_c

106 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ahmed Fendri et al.
International journal of biological macromolecules, 50(5), 1238-1244 (2012-04-26)
A lipolytic activity was located in the chicken uropygial glands, from which a carboxylesterase (CUE) was purified. Pure CUE has an apparent molecular mass of 50 kDa. The purified esterase displayed its maximal activity (200 U/mg) on short-chain triacylglycerols (tributyrin)
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The Biochemical journal, 379(Pt 2), 325-330 (2004-01-22)
The first-order rate constants for the RecA-independent, spontaneous, pH-dependent autocleavage of the lambda cI repressor was measured in the present study at pH 10.6 at 27, 37 and 42 degrees C respectively. Autocleavage of the repressor occurs also at pH
Abhrajyoti Ghosh et al.
Journal of industrial microbiology & biotechnology, 35(8), 825-834 (2008-04-23)
Biotreatment of feather wastes and utilization of the degraded products in feed and foodstuffs has been a challenge. In the present study, we have demonstrated the degradation of feather waste by Bacillus cereus DCUW strain isolated during a functional screening
F Sala et al.
European journal of biochemistry, 112(2), 211-217 (1980-11-01)
A DNA polymerase has been extracted from spinach chloroplasts and purified by chromatography on DEAE-cellulose and hydroxyapatite. A great similarity between the purified chloroplast polymerase and the mammalian mitochondrial DNA polymerase gamma was found by several criteria: preference for the
Toshihiro Takahashi et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 58(5), 557-566 (2003-05-09)
For preparing [18F]labeled compounds free from bromo-compounds for PET (positron emission tomography) studies, we propose the following two processes in which no separation is needed between the fluoro-compound and bromo-compound : (1). the bromo-compound is first converted into O-tosylate, which
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