902527
Amino-PEG5-t-butyl ester
≥95%
Synonym(s):
tert-Butyl-1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate, H2N-PEG5-CH2CH2COOtBu
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C17H35NO7
CAS Number:
Molecular Weight:
365.46
MDL number:
UNSPSC Code:
51171641
Recommended Products
assay
≥95%
form
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index
n/D 1.4534
density
1.4690 g/mL
functional group
amine
ester
storage temp.
−20°C
SMILES string
NCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O
Application
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
related product
Product No.
Description
Pricing
wgk_germany
WGK 3
flash_point_f
No data available
flash_point_c
No data available
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service