930024
Hyaluronic acid adipic dihydrazide (HA-ADH)
Synonym(s):
HA-ADH
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About This Item
Linear Formula:
(C20H33N5O12)n
UNSPSC Code:
12352125
NACRES:
NA.23
Recommended Products
form
solid (Chunks)
Quality Level
color
white to off-white
application(s)
3D bioprinting
storage temp.
2-8°C
Related Categories
General description
Adipic acid dihydrazide is commonly used as a functional group to allow for HA cross-linking to polymers containing aldehyde groups or that are aldehyde-functionalized, like HA-aldehyde or PEG-aldehyde. These biomaterials are attractive for their tunable properties and low cytotoxicity.
Degree of functionalization (50-80%)
Application
Hyaluronic acid (HA) is a ubiquitous extracellular matrix component, which makes it attractive for use in medical applications for it′s biocompatibility and low immunogenicity. HA-based polymers are used to make hydrogels for a wide variety of applications from tissue engineering and regeneration to drug delivery and bioinks for 3D bioprinting. To make hydrogels, HA has to be derivatized with groups that can cross-link to to other functionalized polymers.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering
Chen, et al.
Carbohydrate Polymers, 166, 31-44 (2017)
Yuguo Lei et al.
Biomaterials, 32(1), 39-47 (2010-10-12)
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