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P39605

Sigma-Aldrich

Phthalide

98%

Synonym(s):

1-Isobenzofuranone

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About This Item

Empirical Formula (Hill Notation):
C8H6O2
CAS Number:
Molecular Weight:
134.13
Beilstein/REAXYS Number:
114632
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

form

powder

bp

290 °C (lit.)

mp

71-74 °C (lit.)

SMILES string

O=C1OCc2ccccc12

InChI

1S/C8H6O2/c9-8-7-4-2-1-3-6(7)5-10-8/h1-4H,5H2

InChI key

WNZQDUSMALZDQF-UHFFFAOYSA-N

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fangrui Zhong et al.
Journal of the American Chemical Society, 134(24), 10222-10227 (2012-05-25)
Phthalides were used for the first time in the allylic alkylation reactions with MBH carbonates for the creation of chiral 3,3-disubstituted phthalides. Highly enantioselective regiodivergent synthesis of γ-selective or β-selective allylic alkylation products was achieved by employing bifunctional chiral phosphines
Yun Wei et al.
Journal of chromatography. A, 1284, 53-58 (2013-03-15)
The phthalide compounds of Chuanxiong rhizoma including senkyunolide A, levistolide A, Z-ligustilide and 3-butylidenephthalide, have been reported as the biologically active compounds because of their therapeutic effects. In this work, online high-speed counter-current chromatography coupled with semi-preparative liquid chromatography instrument
Bin Xiao et al.
Bioorganic & medicinal chemistry, 20(16), 4954-4961 (2012-07-24)
On the basis of a marine fungal phthalide (paecilocin A) skeleton, we synthesized 20 analogs and evaluated them for peroxisome proliferator-activated receptor gamma (PPAR-γ) binding and activation. Among these analogs, 6 and 7 had significant PPAR-γ binding activity, and 7
Chang-Yin Li et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 146-160 (2011-02-01)
In this work, the metabolite profiles of Danggui Buxue Tang (DBT) in rat bile and plasma were qualitatively described, and the possible metabolic pathways of DBT were subsequently proposed. Emphasis was put on correlative analysis of metabolite profiling in different
Song-Hwa Chae et al.
Journal of agricultural and food chemistry, 59(15), 8193-8198 (2011-07-07)
The residual contact toxicity of three benzofuranoids (Z)-butylidenephthalide (1), (3S)-butylphthalide (2), and (Z)-ligustilide (3) identified in the rhizome of Cnidium officinale (Apiaceae) to B- and Q-biotype females of Bemisia tabaci was evaluated using a leaf-dip bioassay. Results were compared with

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