07-732
Anti-HDAC6 Antibody, CT
Upstate®, from rabbit
Synonym(s):
Anti-CPBHM, Anti-HD6, Anti-JM21, Anti-PPP1R90
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About This Item
Recommended Products
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... HDAC6(10013)
Specificity
HDAC6
Immunogen
6His-tagged fusion protein corresponding to residues 1031-1215 of human histone deacetylase 6 (HDAC6).
Application
Anti-HDAC6 Antibody, CT is a Rabbit Polyclonal Antibody for detection of HDAC6 also known as histone deacetylase 6 & has been tested in IP & WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Quality
Routinely evaluated by immunoblot.
Target description
134kDa
Linkage
Replaces: MABE546
Physical form
Format: Purified
Protein A purified
Storage and Stability
2 years at -20°C from date of shipment
Analysis Note
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Epigenetic status determines germ cell meiotic commitment in embryonic and postnatal mammalian gonads.
Cell Cycle null
Upregulation of miR-22 promotes osteogenic differentiation and inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by repressing HDAC6 protein expression.
Stem Cells and Development null
Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbens.
Frontiers in Pharmacology null
Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice.
Alcohol null
Acta pharmaceutica Sinica. B, 12(10), 3891-3904 (2022-10-11)
Although the epigenetic regulatory protein histone deacetylase 6 (HDAC6) has been recently implicated in the etiology of Alzheimer's disease (AD), little is known about the role of HDAC6 in the etiopathogenesis of AD and whether HDAC6 can be a potential
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