16-310
Anti-Nitrotyrosine Magnetic Bead Conjugate Antibody
from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity (predicted by homology)
all
technique(s)
immunoprecipitation (IP): suitable
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... NOS1(4842)
General description
Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others.
Immunogen
Nitrated KLH
Application
Anti-Nitrotyrosine Magnetic Bead Conjugate Antibody is an antibody against Nitrotyrosine for use in IP.
Research Category
Signaling
Signaling
Research Sub Category
General Post-translation Modification
General Post-translation Modification
Quality
Evaluated by immunoprecipitation on A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).
Target description
Varies
Physical form
20% slurry; 1x PBS, 0.05% sodium aside.
Sufficient for 10 IPs.
Sufficient for 10 IPs.
Format: Purified
Immunoaffinity Chromatography
Storage and Stability
Stable for 1 year at 2-8°C from date of shipment. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Analysis Note
Control
A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).
A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Andrew Stiff et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 24(8), 1891-1904 (2018-01-25)
Purpose: mAbs are used to treat solid and hematologic malignancies and work in part through Fc receptors (FcRs) on natural killer cells (NK). However, FcR-mediated functions of NK cells from patients with cancer are significantly impaired. Identifying the mechanisms of
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