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539202

Sigma-Aldrich

Protein A, Staphylococcus aureus

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About This Item

UNSPSC Code:
41116133
NACRES:
NA.41

form

lyophilized solid

Quality Level

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

water: soluble

shipped in

ambient

storage temp.

−20°C

General description

Native protein A from Staphylococcus aureus. Provides a versatile and economical means for isolating, detecting, and purifying antibodies. It is especially useful in immunohistochemical studies because, unlike secondary antibodies, it does not bind to cell Fc receptors and, therefore, will not give high background reactions. Strongly reactive with guinea pig; human IgG1, IgG2, and IgG4; mouse IgG2b, and rabbit. Weakly reactive with bovine; human IgA, IgE, and IgM; and mouse IgG3. Nonreactive with goat; horse; human IgD and IgG3; rat; mouse IgG1; and sheep.

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Sjødahl, J. 1976. FEBS Lett.67, 1976.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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Gerard J Nau et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(3), 1503-1508 (2002-01-24)
Understanding the response of innate immune cells to pathogens may provide insights to host defenses and the tactics used by pathogens to circumvent these defenses. We used DNA microarrays to explore the responses of human macrophages to a variety of
Eniko Farkas et al.
Biosensors, 12(2) (2022-02-25)
Bacteria repellent surfaces and antibody-based coatings for bacterial assays have shown a growing demand in the field of biosensors, and have crucial importance in the design of biomedical devices. However, in-depth investigations and comparisons of possible solutions are still missing.
Viktoria Rungelrath et al.
Microbiology spectrum, 9(2), e0088821-e0088821 (2021-10-28)
Staphylococcus aureus is an important human pathogen that can cause a variety of diseases ranging from mild superficial skin infections to life-threatening conditions like necrotizing pneumonia, endocarditis, and septicemia. Polymorphonuclear leukocytes (PMNs; neutrophils in particular herein) are essential for host

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