8.21027
Phthaldialdehyde
for synthesis
Synonym(s):
Phthaldialdehyde, OPA
About This Item
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Quality Level
assay
≥97.5% (GC)
form
solid
autoignition temp.
480 °C
potency
178 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)
pH
7 (20 °C, 53 g/L in H2O)
bp
83-84 °C/1 hPa
mp
52-58 °C
transition temp
flash point 132 °C
solubility
53 g/L
density
1.13 g/cm3 at 20 °C
bulk density
530 kg/m3
storage temp.
2-30°C
InChI
1S/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H
InChI key
ZWLUXSQADUDCSB-UHFFFAOYSA-N
Application
- An investigation of o-phthaldialdehyde as a derivatization reagent and optimization of instrumental parameters for qualitative amino acid profiling via UPLC-UV Detailed examination of o-phthaldialdehyde′s efficiency in amino acid profiling to enhance diagnostic accuracies for metabolic diseases like AKU and PKU (A Aspö - 2023). Access the study.
- Correlation of the Free Amino Nitrogen and Nitrogen by O-Phthaldialdehyde Methods in the Assay of Beer This research correlates nitrogen content measurements in beer using the o-phthaldialdehyde method, discussing its implications for brewing quality control (L Otama, S Tikanoja, H Kane, S Hartikainen, L Kaski - Date not specified). Access the study.
- Turn-on fluorescence detection of glutathione based on o-phthaldialdehyde-assisted SiO2 particles Investigation into a novel fluorometric method for detecting glutathione in supplements using o-phthaldialdehyde and functionalized silica particles (P Nedeljko, M Turel, A Lobnik - 2018). Access the study.
- Biochemical Measures of Neuropathy-Glutathione Assay (GSH) A study on the biochemical assessment of neuropathy by measuring glutathione levels using o-phthaldialdehyde in a methanol solution, emphasizing the methodology′s sensitivity and reliability (E Feldman - 2019). Access the study.
Analysis Note
Melting range (lower value): ≥ 52 °C
Melting range (upper value): ≤ 56 °C
Identity (IR): passes test
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk_germany
WGK 3
flash_point_f
269.6 °F - closed cup
flash_point_c
132 °C - closed cup
Certificates of Analysis (COA)
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