EI10
Pepstatin A
Pepstatin A is an inhibitor of aspartic proteinases such as pepsin, cathepsins D and E
Synonym(s):
Pepstatin
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About This Item
UNSPSC Code:
12352200
eCl@ss:
32160405
NACRES:
NA.77
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General description
M.W.: 685.89
SEQUENCE: isovaleryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA
SEQUENCE: isovaleryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA
Biochem/physiol Actions
Inhibitor Type: Protease Inhibitors
Linkage
Replaces: EI9
Physical form
Purity: >90.0%; pale yellow powder; pH (1% solution) 5.2
Storage and Stability
Maintain dry at -20ºC for up to 18 months after date of receipt. Pepstatin A is soluble in either DMSO or ethanol:acetic acid (9:1) at the concentration of 1 mg/mL. Pepstatin A is insoluble in water as well as aqueous buffer at near neutral pH.
NOTE: Aqueous buffer at a slightly alkaline pH is recommended for diluting the reconstituted solution of either of the above organic solvents. If water or acetic acid is used for dilution, Pepstatin A may precipitate from the solution.
NOTE: Aqueous buffer at a slightly alkaline pH is recommended for diluting the reconstituted solution of either of the above organic solvents. If water or acetic acid is used for dilution, Pepstatin A may precipitate from the solution.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Pepstatin, a new pepsin inhibitor produced by Actinomycetes.
H Umezawa et al.
The Journal of antibiotics, 23(5), 259-262 (1970-05-01)
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