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Supelco

Conjugated (9Z,11E)-Linoleic acid

analytical standard

Synonym(s):

(9Z,11E)-9,11-Octadecadienoic acid, 9Z,11E-CLA, Bovinic acid, Linoleic acid (9-cis, 11-trans)

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About This Item

Empirical Formula (Hill Notation):
C18H32O2
CAS Number:
Molecular Weight:
280.45
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

biological source

synthetic

Quality Level

grade

analytical standard

assay

≥96.0% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.478-1.483

format

neat

functional group

carboxylic acid

storage temp.

−20°C

SMILES string

CCCCCC\C=C\C=C/CCCCCCCC(O)=O

InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h7-10H,2-6,11-17H2,1H3,(H,19,20)/b8-7+,10-9-

InChI key

JBYXPOFIGCOSSB-GOJKSUSPSA-N

General description

Conjugated Linoleic acid is a naturally occurring fatty acid. It has anti-cancer, anti-atherogenic and anti-diabetic properties. 9Z,11E is a geometric isomer which belongs to linoleate group.

Application

It was may be used for HPLC-ESI-MS/MS analysis to quantify and also structural analysis of nitrated species of CLA.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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Conjugated linoleic acid is a preferential substrate for fatty acid nitration.
Bonacci G
The Journal of Biological Chemistry, 287(53), 44071-44082 (2012)
Yu Y, Correll PH, Vanden Heuvel JP
Biochimica et Biophysica Acta, 1581(3), 89-99 (2002)
Sanjay Basak et al.
Biochimica et biophysica acta, 1831(4), 834-843 (2013-01-29)
A number of studies have been carried out to examine the biological function of conjugated linoleic acid (CLA) and its potential health benefits. However, not much is known about how CLA isomers mediate their effect on angiogenesis and vascularization during
José M Pestana et al.
Meat science, 90(3), 819-827 (2011-12-03)
The influence of slaughter season and muscle type on the detailed fatty acid composition, including conjugated linoleic acid isomers, and contents of total cholesterol and lipid-soluble antioxidant vitamins (α-tocopherol and β-carotene) in Mirandesa-PDO veal was assessed. Mirandesa purebred calves (n=29)
Elena Giordano et al.
Nutrition research (New York, N.Y.), 31(11), 855-862 (2011-11-29)
Conjugated linoleic acid (CLA) is a polyunsaturated fatty acid that has numerous biologic activities. Previous studies in rodents demonstrated that chronic intake of CLA t10,c12 or CLA c9,t11 isomers perturbs the metabolism of retinoids (vitamin A and its derivatives). Specifically

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