O5632
Linoleic acid, conjugated methyl ester
Synonym(s):
CLA methyl ester, Octadecadienoic acid, conjugated, methyl ester
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About This Item
Recommended Products
biological source
plant (safflower)
Quality Level
assay
≥99% (GC)
form
liquid
technique(s)
GC/MS: suitable
HPLC: suitable
impurities
≤1% Linoleic acid methyl ester
functional group
carboxylic acid
ester
lipid type
omega FAs
shipped in
ambient
storage temp.
−20°C
General description
Conjugated linoleic acid (CLA) describes the positional and geometric isomers of C18:2 fatty acids (FA) with a conjugated double bond. cis-9, trans-11 CLA are considered as the major isomers of CLA, based on in vitro experiments and animal studies in milk. The major source of CLA in human diet is the ruminant fat.
Application
Linoleic acid, conjugated methyl ester (CLA) has been used as a standard for the determination of isomers of CLA in milk samples by high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry. It has also been used in the production of sn-1,3 diacyl glycerol.
Biochem/physiol Actions
Conjugated linoleic acid (CLA) isomers as supplements inhibit the growth of numerous human cancer cell lines. It also possesses immunostimulant properties, prevents diabetes and reduces atherosclerosis.
Other Notes
A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acid methyl esters. Isomer ratio may vary from lot to lot.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
Certificates of Analysis (COA)
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TheScientificWorldJournal, 2014, 821904-821904 (2014-02-14)
This study was conducted to compare fatty acid composition and content of conjugated linoleic acid (CLA) in different regions of sheep carcasses. Lambs of the Dağlıç breed were used for this purpose. Subsequent to a 68-day period of intensive fattening
Examination of the persistency of milk fatty acid composition responses to plant oils in cows given different basal diets, with particular emphasis on trans-C 18: 1 fatty acids and isomers of conjugated linoleic acid
Animal Science Journal = Nihon Chikusan Gakkaiho, 82(4), 479-492 (2006)
Journal of dairy science, 102(11), 10483-10499 (2019-09-10)
The aims of this work were to determine the effect of upland origin on milk composition when comparing similar lowland and upland production system and to highlight the factors responsible for the added value of upland milk from commercial farms.
Examination of the persistency of milk fatty acid composition responses to fish oil and sunflower oil in the diet of dairy cows
Journal of Dairy Science, 89(2), 714-732 (2006)
Effect of incremental levels of sunflower-seed oil in the diet on ruminal lipid metabolism in lactating cows
The British Journal of Nutrition, 99(5), 971-983 (2008)
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