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Supelco

Daidzin

analytical standard

Synonym(s):

4′,7-Dihydroxyisoflavone 7-glucoside, Daidzein 7-glucoside, Daidzein-7-O-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C21H20O9
CAS Number:
552-66-9
Molecular Weight:
416.38
Beilstein/REAXYS Number:
59741
MDL number:
MFCD00017466
UNSPSC Code:
85151701
PubChem Substance ID:
329756285
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@@H](Oc2ccc3C(=O)C(=COc3c2)c4ccc(O)cc4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1

InChI key

KYQZWONCHDNPDP-QNDFHXLGSA-N

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General description

Daidzin is a plant isoflavone glycoside and a potent inhibitor of human mitochondrial aldehyde dehydrogenase (ALDH-I).

Application

Daidzin may be used as a reference standard in the determination of daidzin in the root of Pueraria lobate using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Daidzin was the most potent isoflavone glycoside tested in modulating differentiation of bone marrow stromal cells toward osteoblasts and away from adipocytes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

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Sigma-Aldrich

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Preventive effects of the plant isoflavones, daidzin and genistin, on bone loss in ovariectomized rats fed a calcium-deficient diet.
Ishida H, et al.
Biological & Pharmaceutical Bulletin, 21(1), 62-66 (1998)
Determination of puerarin, daidzin and daidzein in root of Pueraria lobata of different origin by HPLC.
SWJ, et al.
Zhongguo Zhong Yao Za Zhi = Zhongguo zhongYao ZaZhi = China Journal of Chinese Materia Medica, 28(1), 49-51 (2003)
Daidzin: a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase.
Keung MW and Vallee LB
Proceedings of the National Academy of Sciences of the USA, 90(4), 1247-1251 (1993)
Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin.
Uesugi T, et al.
Biological & Pharmaceutical Bulletin, 24(4), 368-372 (2001)
Benyakan Pongkitwitoon et al.
Planta medica, 76(8), 831-836 (2009-12-25)
Pueraria candollei (White Kwao Khuer) is a medicinal plant containing puerarin, daidzin, genistin, daidzein, and genistein as major isoflavonoids used for its rejuvenating and estrogenic effects. In order to analyze these compounds, a single enzyme-linked immunosorbent assay (ELISA) for total
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