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69545

Supelco

Kaempferide

analytical standard

Synonym(s):

3,5,7-Trihydroxy-4′-methoxyflavone, KF, 4′-Methoxy-3,5,7-trihydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C16H12O6
CAS Number:
491-54-3
Molecular Weight:
300.26
Beilstein/REAXYS Number:
305378
EC Number:
207-738-4
MDL number:
MFCD00016771
UNSPSC Code:
85151701
PubChem Substance ID:
329761743
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2

InChI

1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3

InChI key

SQFSKOYWJBQGKQ-UHFFFAOYSA-N

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General description

Kaempferide is a naturally occurring, O-methylated flavonol found in Kaempferia galanga. It exhibits a variety of pharmacological effects such as anti-inflammatory, anti-viral, anti-oxidant, anti-bacterial and antitumor properties.

Application

Kaempferide may be used as an analytical reference standard for the quantification of the analyte in propolis and traditional Chinese medicine Zuo Gui Wan using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: arnica silybum

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Cuiping Zhang et al.
Journal of food science, 82(7), 1602-1607 (2017-06-01)
Brazilian green propolis is known as an appreciable natural antioxidant with abundant polyphenolic compounds. For quality control, a fingerprint-efficacy study of Brazilian green propolis was carried out in this work. Chemical fingerprints of Brazilian green propolis from 22 different sources
Kaempferide prevents titanium particle induced osteolysis by suppressing JNK activation during osteoclast formation
Jiao Z, et al.
Scientific Reports, 7(1) (2017)
Madoka Takashima et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 132, 110669-110669 (2019-07-13)
Propolis is a sticky dark-colored substance produced by honey bees and comprises resin, balsam, wax, essential and aromatic oils, pollen, and several other substances; it is used in food and beverages to improve health and prevent diseases. We studied the
Selective analysis of phenolic compounds in propolis by HPLC?MS/MS
Medana C, et al.
Phytochemical Analysis, 19(1), 32-39 (2008)
Kaempferide prevents titanium particle induced osteolysis by suppressing JNK activation during osteoclast formation
Jiao Z, et al.
Scientific reports, 7(1) (2017)
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