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Supelco

Luteolin

analytical standard

Synonym(s):

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
491-70-3
Molecular Weight:
286.24
Beilstein/REAXYS Number:
292084
EC Number:
207-741-0
MDL number:
MFCD00017309
UNSPSC Code:
85151701
PubChem Substance ID:
329764132

grade

analytical standard

Quality Level

100

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

~330 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

InChI key

IQPNAANSBPBGFQ-UHFFFAOYSA-N

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General description

Luteolin is a naturally occurring flavone, readily present in vegetables. It may possess many biological properties like anti-tumor activity against condition of skin papilloma.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

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Sigma-Aldrich

SMB00540

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USP

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PHR2198

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Luteolin 7-rutinoside ≥95% (LC/MS-ELSD)

Sigma-Aldrich

SMB00200

Luteolin 7-rutinoside

Bonavida B
Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy (2008)
Dietary luteolin attenuates chronic liver injury induced by mercuric chloride via the Nrf2/NF-?B/P53 signaling pathway in rats
Zhang H, et al.
Oncotarget, 8(25) (2017)
Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo
Zheng S, et al.
Oncotarget, 8(37) (2017)
Lien Verschooten et al.
PloS one, 7(10), e48264-e48264 (2012-10-31)
Flavonoids are widely proposed as very interesting compounds with possible chemopreventive and therapeutic capacities. In this study, we showed that in vitro treatment with the flavonoid Luteolin induced caspase-dependent cell death in a model of human cutaneous squamous cell carcinoma
Poyil Pratheeshkumar et al.
PloS one, 7(12), e52279-e52279 (2013-01-10)
Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid found in fruits and vegetables. We studied the antiangiogenic activity of luteolin using in vitro
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