Skip to Content
MilliporeSigma
All Photos(1)

Documents

900688

Sigma-Aldrich

Methanol

≥99.92%, suitable for UHPLC, mass spectrometry (MS)

Synonym(s):

Methyl alcohol

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3OH
CAS Number:
Molecular Weight:
32.04
Beilstein/REAXYS Number:
1098229
EC Number:
MDL number:
UNSPSC Code:
12191601
NACRES:
NA.05

product name

Methanol, UHPLC, suitable for mass spectrometry (MS)

agency

suitable for ASTM® 7968
suitable for ASTM® 7979
suitable for DIN 38407-42
suitable for EPA 1621
suitable for EPA 1633
suitable for EPA 533
suitable for EPA 537.1
suitable for EPA 8327
suitable for EPA ACB B21-02
suitable for EPA ACB B23-05b
suitable for EPA OTM-45
suitable for GB 31604.35-2016
suitable for GB 5009.253-2016
suitable for ISO 21675 2019
suitable for ISO 25101
suitable for ISO/CEN 15968-2010

Quality Level

reg. compliance

suitable for FDA C-010.02

vapor density

1.11 (vs air)

vapor pressure

410 mmHg ( 50 °C)
97.68 mmHg ( 20 °C)

assay

≥99.92%

form

liquid

autoignition temp.

725 °F

expl. lim.

36 %

technique(s)

UHPLC: suitable
mass spectrometry (MS): suitable

refractive index

n20/D 1.329 (lit.)

bp

64.7 °C (lit.)

mp

−98 °C (lit.)

density

0.791 g/mL at 25 °C (lit.)

application(s)

food and beverages

format

neat

SMILES string

CO

InChI

1S/CH4O/c1-2/h2H,1H3

InChI key

OKKJLVBELUTLKV-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Methanol, a primary aliphatic alcohol, is an organic solvent that finds numerous uses in industrial applications. It is commonly used as an analytical standard, an extractant medium and as a mobile phase additive in various chromatographic separations.

Application

Methanol may be used:
  • As a stripping solvent to desorb pesticides after their extraction using hollow fiber liquid phase microextraction (HF-LPME), prior to the determination of the analytes in alcoholic beverages by ultra-high pressure liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS).
  • In the preparation of a mobile phase for the determination of phenolic acids in beverages by UPLC–MS/MS.
  • As an extraction solvent for the quantification of bisphenol-type endocrine disrupting compounds in food-contact recycled-paper materials by UPLC coupled to high resolution MS.

Legal Information

ASTM is a registered trademark of American Society for Testing and Materials

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

wgk_germany

WGK 2

flash_point_f

closed cup

flash_point_c

closed cup


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 7

1 of 7

Methanol suitable for HPLC, ≥99.9%

Sigma-Aldrich

34860

Methanol

Methanol gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur

Supelco

1.06007

Methanol

Water solution contains 0.1 % (v/v) formic acid, for UHPLC, suitable for mass spectrometry (MS)

Sigma-Aldrich

900687

Water solution

Methanol for gas chromatography MS SupraSolv®

Supelco

1.00837

Methanol

Acetonitrile solution contains 0.1 % (v/v) formic acid, for UHPLC, suitable for mass spectrometry (MS)

Sigma-Aldrich

900686

Acetonitrile solution

Methanol ACS spectrophotometric grade, ≥99.9%

Sigma-Aldrich

154903

Methanol

Methanol for Purge & Trap SupraSolv®

Supelco

557225

Methanol

Rapid analysis of phenolic acids in beverages by UPLC-MS/MS
Gruz J, et al.
Food Chemistry, 111(3), 789-794 (2008)
Fabio Gosetti et al.
Food chemistry, 136(2), 617-623 (2012-11-06)
The study deals with the identification of the degradation products formed by simulated sunlight photoirradiation in a commercial beverage that contains Allura Red AC dye. An UHPLC-MS/MS method, that makes use of hybrid triple quadrupole/linear ion trap, was developed. In
Comparison of ultra-performance liquid chromatography and high-performance liquid chromatography for the determination of priority pesticides in baby foods by tandem quadrupole mass spectrometry.
Leandro CC, et al.
Journal of Chromatography A, 1103(1), 94-101 (2006)
Clayton Evert et al.
ACS infectious diseases, 5(3), 385-393 (2019-01-10)
Stable isotope probing (SIP) has emerged as a powerful tool to address key questions about microbiota structure and function. To date, diverse isotopically labeled substrates have been used to characterize in situ growth activity of specific bacterial taxa and have

Articles

A simplified LC-MS/MS method to determine glyphosate and related compounds using a Supel™ Carbon LC U/HPLC column for stability under higher pH conditions and sufficient retention for the polar analytes in the presence of methanol as an extraction solvent.

A comprehensive high performance liquid chromatography-diode array detection (HPLC-DAD) workflow for the analysis of 14 cannabinoids in hemp bud extracts within 10 minutes using robust Chromolith® monolithic silica HPLC columns with low column back pressure.

A complete workflow for the HPLC separation of 17 cannabinoids in different cannabis products using Ascentis® Express C18 Column in a shorter run time with retention time stability. Learn more here.

An overview of gradient HPLC-based analysis of cannabinoids, optimized for key method parameters such as column temperature, mobile phase pH, and methanol as low-cost organic modifier. Learn more here.

See All

Protocols

HPLC separation of 17 important cannabinoids including CBD, delta 9 THC and THCA. Read the application note

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service