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BP1075

Mesalazine

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

5-Aminosalicylic acid, 5-AS, 5-Amino-2-hydroxybenzoic acid, Mesalamine

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About This Item

Linear Formula:
H2NC6H3-2-(OH)CO2H
CAS Number:
89-57-6
Molecular Weight:
153.14
Beilstein/REAXYS Number:
2090421
MDL number:
MFCD00007877
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

mesalazine, mesalamine

form

powder

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

275-280 °C (dec.) (lit.)

application(s)

pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

Nc1ccc(O)c(c1)C(O)=O

InChI

1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)

InChI key

KBOPZPXVLCULAV-UHFFFAOYSA-N

Gene Information

human ... ALOX5(240) , PPARG(5468) , PTGS1(5742) , PTGS2(5743)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Mesalazine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Mesalazine Suppositories
  • Mesalazine Foam Enema
  • Mesalazine Enema
  • Mesalazine Prolonged-release Tablets
  • Mesalazine Gastro-resistant Tablets
  • Mesalazine Prolonged-release Granules
    • 5-Aminosalicylic acid is a peroxidase substrate suitable for use in ELISA procedures. This substrate produces a soluble end product that is brown in color and can be read spectrophotometrically at 450 nm. The reaction may be stopped with 3 N NaOH and read at 550 nm.

    Packaging

    Unit quantity: 125 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    pictograms

    Exclamation mark
    GHS07

    signalword

    Warning

    Hazard Classifications

    Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

    target_organs

    Respiratory system

    Storage Class

    11 - Combustible Solids

    wgk_germany

    WGK 2

    flash_point_f

    536.0 °F

    flash_point_c

    280 °C

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