Skip to Content
MilliporeSigma
All Photos(1)

Documents

PHR1315

Supelco

Valsartan

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Valsartan, N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C24H29N5O3
CAS Number:
137862-53-4
Molecular Weight:
435.52
MDL number:
MFCD00865840
UNSPSC Code:
41116107
PubChem Substance ID:
329823301
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to BP 1161
traceable to Ph. Eur. Y0001132
traceable to USP 1708762

API family

valsartan

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCC(=O)N(Cc1ccc(cc1)-c2ccccc2-c3nnn[nH]3)[C@@H](C(C)C)C(O)=O

InChI

1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1

InChI key

ACWBQPMHZXGDFX-QFIPXVFZSA-N

Gene Information

human ... AGTR1(185)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Valsartan is an orally active specific angiotensin II receptor blocker used for the treatment of hypertension.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Valsartan may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometry.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2970 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation markHealth hazard
GHS07,GHS08

signalword

Warning

Hazard Classifications

Repr. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD3659
LRAC2970
LRAD0397
LRAA9111
LRAC2970

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 9

1 of 9

Valsartan Related Compound A United States Pharmacopeia (USP) Reference Standard

USP

1708773

Valsartan Related Compound A

LBQ657 ≥97% (HPLC)

Sigma-Aldrich

SML2064

LBQ657

Sacubitril calcium salt ≥98% (HPLC)

Sigma-Aldrich

SML1380

Sacubitril calcium salt

Telmisartan Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1855

Telmisartan

Sodium diatrizoate hydrate ≥98.0%

Sigma-Aldrich

S4506

Sodium diatrizoate hydrate

Valsartan for peak identification European Pharmacopoeia (EP) Reference Standard

Y0001131

Valsartan for peak identification

Losartan Potassium Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1602

Losartan Potassium

Hydrochlorothiazide Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1032

Hydrochlorothiazide

Candesartan Cilexetil Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1854

Candesartan Cilexetil

Stability indicating RP-HPLC method for determination of valsartan in pure and pharmaceutical formulation
Patro SK, et al.
Journal of Chemistry, 7(1), 246-252 (2010)
Stability-indicating UPLC method for determination of Valsartan and their degradation products in active pharmaceutical ingredient and pharmaceutical dosage forms
Krishnaiah Ch, et al.
Journal of Pharmaceutical and Biomedical Analysis, 53(3), 483-489 (2010)
Simultaneous spectrophotometric determination of valsartan and ezetimibe in pharmaceuticals
Ramachandran S, et al.
Tropical Journal of Pharmaceutical Research, 10(6), 809-815 (2011)
Simultaneous determination of valsartan and hydrochlorothiazide in tablets by RP-HPLC
Tian FD, et al.
Indian Journal of Pharmaceutical Sciences, 70(3), 372-372 (2008)
Genyang Cheng et al.
Nephrology (Carlton, Vic.), 20(2), 77-84 (2014-11-02)
The current standard treatment for IgA nephropathy relies on steroid and/or immunosuppressive therapy and angiotensin converting enzyme inhibitors (ACEI) or angiotensin receptor blocker (ARB). This study examines the benefits and safety of combining valsartan with clopidogrel and leflunomide as a
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service