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PHR1357

Supelco

Histamine Dihydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

2-(4-Imidazolyl)ethylamine dihydrochloride

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About This Item

EC Number:
200-298-4
UNSPSC Code:
41116107

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

agency

traceable to Ph. Eur. H0600000
traceable to USP 1309009

API family

histamine

CofA

current certificate can be downloaded

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Related Categories

General description

Histamine Dihydrochloride is a derivative of histamine, which is implicated in tumor cell apoptosis and prevents the relapse of acute myeloid leukemia in patients. It prevents the formation of ROS (reactive oxygen species) and inhibits the activation of T cells and natural killer cells.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA1410 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation markHealth hazard
GHS07,GHS08

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD4313
LRAC4361
LRAA9150
LRAA1410

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Markus Lacorn et al.
Journal of AOAC International, 102(5), 1472-1491 (2019-04-25)
Background: RIDASCREEN® Histamine (enzymatic) is an enzymatic test kit for quantification of histamine in fresh fish, canned fish, fish meal, cheese, and wine. Methods: Fish products are extracted with boiling water, while cheese is extracted with water, and the extract

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