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Y0000384

All-rac-alpha-tocopheryl acetate for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

DL-α-Tocopherol acetate, Vitamin E acetate, all-rac-α-Tocopheryl acetate

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About This Item

Empirical Formula (Hill Notation):
C31H52O3
CAS Number:
7695-91-2
Molecular Weight:
472.74
Beilstein/REAXYS Number:
97512
MDL number:
MFCD00072042
UNSPSC Code:
41116107
PubChem Substance ID:
329830929
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP

API family

tocopherol

form

solid

manufacturer/tradename

EDQM

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

density

0.96 g/mL at 20 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
All-rac-alpha-tocopheryl acetate, the ester of all-rac-alpha-tocopherol, is a commercial form of vitamin E. It is responsible for the protection of phenol groups of the parent tocopherol against oxidation.

Application

All-rac-alpha-tocopheryl acetate for peak identification may be used as an EP reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

No data available

flash_point_c

No data available

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α-Tocopherol European Pharmacopoeia (EP) Reference Standard

T1550000

α-Tocopherol

(+)-α-Tocopherol acetate oil or semi-solid, ~1360 IU/g

Sigma-Aldrich

T3001

(+)-α-Tocopherol acetate

Millipore

Millipore

613424

Tocopherol Set

(±)-α-Tocopherol tested according to Ph. Eur.

Sigma-Aldrich

90669

(±)-α-Tocopherol

Retinol acetate European Pharmacopoeia (EP) Reference Standard

R0300000

Retinol acetate

(±)-α-Tocopherol synthetic, ≥96% (HPLC)

Sigma-Aldrich

T3251

(±)-α-Tocopherol

Succinic Acids?Advances in Research and Application: 2013 Edition: ScholarlyBrief
Acton QA
Succinic Acids?Advances in Research and Application (2013)
All-rac-alpha-tocopherol acetate is a better vitamin E source than all-rac-alpha-tocopherol succinate for broilers
Jensen S, et al.
The Journal of Nutrition, 129(7), 1355-1360 (1999)
all-rac-?-Tocopheryl acetate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 129(7), 3802-3804 (2011)
Adis Tasanarong et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 28(2), 337-344 (2013-01-15)
Contrast-induced acute kidney injury (CI- AKI) increases the likelihood of patient morbidity and mortality following coronary procedures. Volume supplement with saline is the standard treatment to prevent CI-AKI. Additional antioxidant prophylaxis has often yielded conflicting results. The present study was
Yin Yin Thoo et al.
Food chemistry, 138(2-3), 1215-1219 (2013-02-16)
The synergistic antioxidant effects of ethanolic extracts of Centella asiatica (CE), and α-tocopherol have been studied. The types of interactions exhibited by CE and α-tocopherol combined at different ratios were measured using three assays: 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS) radical-scavenging
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