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T3376

Sigma-Aldrich

DL-α-Tocopherol acetate

≥96% (HPLC)

Synonym(s):

Vitamin E acetate, all-rac-α-Tocopheryl acetate

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About This Item

Empirical Formula (Hill Notation):
C31H52O3
CAS Number:
7695-91-2
Molecular Weight:
472.74
Beilstein/REAXYS Number:
97512
EC Number:
231-710-0
MDL number:
MFCD00072042
UNSPSC Code:
12352205
PubChem Substance ID:
24900133
NACRES:
NA.79

biological source

synthetic (organic)

Quality Level

200

assay

≥96% (HPLC)

form

viscous liquid

technique(s)

HPLC: suitable

color

colorless to dark yellow

density

0.96 g/mL at 20 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1

InChI key

ZAKOWWREFLAJOT-CEFNRUSXSA-N

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General description

α-Tocopherol is a predominant form of vitamin E in human and animal tissues and also in leaf chloroplasts. It is the major form in supplements. DL-α-Tocopherol acetate is considered as the only storage form of vitamin E.

Application

DL-α-Tocopherol acetate has been used to study it effect on blood pressure and lipidic profile in streptozotocin-induced diabetes mellitus rats. It has also been used as a standard in α-tocopherol analysis using plasma sample and mature fresh tobacco leaves.

Biochem/physiol Actions

Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

No data available

flash_point_c

No data available

ppe

Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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All-rac-alpha-tocopheryl acetate for peak identification European Pharmacopoeia (EP) Reference Standard

Y0000384

All-rac-alpha-tocopheryl acetate for peak identification

all-rac-α-Tocopheryl acetate (Vitamin E acetate), EMPROVE® ESSENTIAL, Ph. Eur., BP, USP, FCC

SAFC

5.00952

all-rac-α-Tocopheryl acetate

Vitamin E dry powder, (50 g all-rac-a-tocopheryl acetate in 100 g subst), EMPROVE® ESSENTIAL, Ph. Eur., BP, USP

SAFC

5.00859

Vitamin E

(±)-α-Tocopherol analytical standard

Supelco

47783

(±)-α-Tocopherol

Retinyl acetate synthetic, crystalline solid or supercooled liquid

Sigma-Aldrich

R4632

Retinyl acetate

High levels of dietary unsaturated fat decrease alpha-tocopherol content of whole body, liver, and plasma of chickens without variations in intestinal apparent absorption
Villaverde C, et al.
Poultry Science, 87(3), 497-505 (2008)
Rachel M Taylor et al.
PloS one, 11(3), e0151665-e0151665 (2016-03-24)
The current National Research Council (NRC) selenium (Se) requirement for the turkey is 0.2 μg Se/g diet. The sequencing of the turkey selenoproteome offers additional molecular biomarkers for assessment of Se status. To determine dietary Se requirements using selenoprotein transcript
Brandon L Pearson et al.
Nature communications, 7, 11173-11173 (2016-04-01)
Environmental factors, including pesticides, have been linked to autism and neurodegeneration risk using retrospective epidemiological studies. Here we sought to prospectively identify chemicals that share transcriptomic signatures with neurological disorders, by exposing mouse cortical neuron-enriched cultures to hundreds of chemicals
Nutrient Requirements of Fish and Shrimp (2011)
gamma-Tocopherol, the major form of vitamin E in the US diet, deserves more attention
Jiang Q, et al.
American Journal of Clinical Nutrition, 74(6), 714-722 (2001)
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Dietary Antioxidants

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