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Y0001593

Dexamethasone for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dexamethasone, (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

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About This Item

Empirical Formula (Hill Notation):
C22H29FO5
CAS Number:
50-02-2
Molecular Weight:
392.46
Beilstein/REAXYS Number:
2066651
MDL number:
MFCD00064136
UNSPSC Code:
41116107
PubChem Substance ID:
329831500
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

agency

EP

API family

dexamethasone

form

powder

manufacturer/tradename

EDQM

storage condition

protect from light

mp

262-264 °C (lit.)
262-264 °C

solubility

water: <0.1 g/L

application(s)

pharmaceutical (small molecule)

format

neat

shipped in

ambient

storage temp.

2-8°C

SMILES string

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

InChI

1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

InChI key

UREBDLICKHMUKA-CXSFZGCWSA-N

Gene Information

human ... NR3C1(2908)

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Related Categories

General description

Dexamethasone belongs to the class of synthetic glucocorticoid steroid drugs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone is used as an EP referencs standard to quantify the analyte in pharmaceutical formulations using liquid chromatography (LC) technique.

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

1177000

Dexamethasone phosphate, United States Pharmacopeia (USP) Reference Standard

D0710000

Dexamethasone acetate, European Pharmacopoeia (EP) Reference Standard

D0700000

Dexamethasone, European Pharmacopoeia (EP) Reference Standard

Y0000511

Dexamethasone isonicotinate for impurity C identification, European Pharmacopoeia (EP) Reference Standard

Y0000538

Dexamethasone isonicotinate, European Pharmacopoeia (EP) Reference Standard

Y0001177

Dexamethasone for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001169

Dexamethasone acetate impurity E, European Pharmacopoeia (EP) Reference Standard

1176506

Dexamethasone acetate, United States Pharmacopeia (USP) Reference Standard

1176007

Dexamethasone, United States Pharmacopeia (USP) Reference Standard

PHR1526

Dexamethasone, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1527

Dexamethasone Acetate, Pharmaceutical Secondary Standard; Certified Reference Material

BP578

Dexamethasone, British Pharmacopoeia (BP) Assay Standard

PHR1628

Dexamethasone Phosphate, Pharmaceutical Secondary Standard; Certified Reference Material

BP811

Dexamethasone impurity standard, British Pharmacopoeia (BP) Reference Standard

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H360FD

Hazard Classifications

Repr. 1B

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Lot/Batch Number

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Sigma-Aldrich

D2915

Dexamethasone-Water Soluble

Dexamethasone powder, BioReagent, suitable for cell culture, &#8805;97%

Sigma-Aldrich

D4902

Dexamethasone

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