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G5001

Sigma-Aldrich

DL-Glyceraldehyde

≥90% (GC)

Synonym(s):

α,β-Dihydroxypropionaldehyde, 2,3-Dihydroxypropanal

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About This Item

Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic

Quality Level

assay

≥90% (GC)

form

powder

color

white to off-white

mp

145  °C ((293 °F ))

solubility

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

room temp

SMILES string

[H]C(=O)C(O)CO

InChI

1S/C3H6O3/c4-1-3(6)2-5/h1,3,5-6H,2H2

InChI key

MNQZXJOMYWMBOU-UHFFFAOYSA-N

General description

Glyceraldehyde is a simple monosaccharide. Based on the number of carbon atoms and the type of carbonyl group present, glyceraldehyde belongs to subgroup triose. It is a colourless and sweet compound.

Application

DL-Glyceraldehyde has been used:
  • as modifying reagent in the preparation of crystallization solution
  • as a substrate to measure aldose reductase activity
  • in the preparation of d/l-glyceraldehyde stock to determine the specific activity of GAPDH (glyceraldehyde 3-phosphate dehydrogenase)

Biochem/physiol Actions

Glyceraldehyde serves as an efficient cross-linking agent and is considered non-toxic. It is an intermediate of a number of metabolic such as glycolysis and pentose phosphate pathway.

Other Notes

DL-Glyceraldehyde is a substrate for the enzyme aldose reductase.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gemma Sangüesa et al.
European journal of nutrition, 58(3), 1283-1297 (2018-03-09)
Sugar-sweetened beverage intake is a risk factor for insulin resistance, dyslipidemia, fatty liver, and steatohepatitis (NASH). Sub-chronic supplementation of liquid fructose, but not glucose, in female rats increases liver and plasma triglycerides without inflammation. We hypothesized that chronic supplementation of
Raman and infrared spectroscopy of carbohydrates: a review
Wiercigroch E, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 185(5), 317-335 (2017)
Chethan Sampath et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 502-513 (2016-09-30)
Hyperglycemic stress activates polyol pathway and aldose reductase (AR) key enzyme responsible for generating secondary complications during diabetes. In this study the therapeutic potential of phloretin, epigallocatechin 3-gallate (EGCG) and [6]-gingerol were evaluated for anti-glycating and AR inhibitory activity in
GAPDH and Intermediary Metabolism
GAPDH: Biological Properties and Diversity, 37-59 (2012)
Stabilization of scleral collagen by glycerol aldehyde cross-linking
N.A.Danilov, et al.
Biochimica et Biophysica Acta, 1780(5), 764-772 (2008)

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