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GHS1128

Sigma-Aldrich

Hematoxylin Solution, Gill No. 1

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About This Item

MDL number:
MFCD00078111
UNSPSC Code:
41116124
PubChem Substance ID:
24895387
NACRES:
NA.47

form

solution

Quality Level

500

shelf life

Expiry date on the label.

IVD

for in vitro diagnostic use

concentration

2 g/L

pH

2.5-3.5

application(s)

hematology
histology

storage temp.

room temp

SMILES string

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

InChI key

WZUVPPKBWHMQCE-XJKSGUPXSA-N

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Application

Gill No. 1 formulation is used as a progressive cytology stain. Used with hematoxylin and eosin staining.

Other Notes

2 g/L certified hematoxylin

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

hcodes

H302,H373

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2 Oral

target_organs

Kidney

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Michael J Turner et al.
Journal of neuroimmunology, 285, 4-12 (2015-07-23)
Alemtuzumab, a monoclonal antibody directed against human CD52, is used in the treatment of MS. To characterize the impact of anti-CD52 administration, a monoclonal antibody to mouse CD52 (anti-muCD52) was generated and evaluated in EAE mouse models of MS. A
Eleni Maniati et al.
Cell reports, 30(2), 525-540 (2020-01-16)
Although there are many prospective targets in the tumor microenvironment (TME) of high-grade serous ovarian cancer (HGSOC), pre-clinical testing is challenging, especially as there is limited information on the murine TME. Here, we characterize the TME of six orthotopic, transplantable syngeneic
Li-Gen Lin et al.
Journal of medicinal chemistry, 51(15), 4419-4429 (2008-07-10)
Protein tyrosine kinase (PTK) inhibitors represent emerging therapeutics for cancer chemoprevention. In our study, hematoxylin (26) was identified as one of the most remarkable c-Src inhibitors in an orthogonal compound-mixing library (32200 compounds) by using an ELISA-based automated high-throughput screening
Hideki Ishii et al.
Bioorganic & medicinal chemistry letters, 22(3), 1469-1474 (2012-01-17)
SAR studies for the exploration a novel class of anti-human immunodeficiency virus type 1 (HIV-1) agents based on the hematoxylin structure (1) are described. The systematic deoxygenations of 1 including asymmetric synthesis were conducted to obtain a compound showing high
Devalingam Mahalingam et al.
Autophagy, 10(8), 1403-1414 (2014-07-06)
We previously reported that inhibition of autophagy significantly augmented the anticancer activity of the histone deacetylase (HDAC) inhibitor vorinostat (VOR) through a cathepsin D-mediated mechanism. We thus conducted a first-in-human study to investigate the safety, preliminary efficacy, pharmacokinetics (PK), and

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