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I9148

Sigma-Aldrich

Sodium iodoacetate

≥98%, BioUltra

Synonym(s):

Iodoacetic acid sodium salt

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About This Item

Linear Formula:
ICH2COONa
CAS Number:
305-53-3
Molecular Weight:
207.93
Beilstein/REAXYS Number:
4009322
EC Number:
206-165-7
MDL number:
MFCD00002686
UNSPSC Code:
12352202
PubChem Substance ID:
24896151
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

200

product line

BioUltra

assay

≥98%

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

208 °C (dec.) (lit.)

solubility

H2O: 0.5 M, clear, colorless

anion traces

sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.001%
Fe: ≤0.0005%
K: ≤0.02%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

−20°C

SMILES string

[Na+].[O-]C(=O)CI

InChI

1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

InChI key

AGDSCTQQXMDDCV-UHFFFAOYSA-M

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Related Categories

Application

Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains.
Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease.

pictograms

CorrosionSkull and crossbones
GHS05,GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

406.4 °F

flash_point_c

208 °C

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Helena Akerud et al.
American journal of physiology. Endocrinology and metabolism, 297(6), E1414-E1419 (2009-10-15)
It is generally believed that a relationship exists between muscle fatigue and intracellular accumulation of lactate. This reasoning is relevant to obstetrical issues. Myocytes in uterus work together during labor, and the contractions need to be strong and synchronized for
Mohammed Gagaoua et al.
Journal of agricultural and food chemistry, 63(30), 6799-6809 (2015-07-15)
Many studies on color biochemistry and protein biomarkers were undertaken in post-mortem beef muscles after ≥24 hours. The present study was conducted on Longissimus thoracis muscles of 21 Blond d'Aquitaine young bulls to evaluate the relationships between protein biomarkers present
Joon Shik Yoon et al.
American journal of physical medicine & rehabilitation, 94(8), 644-648 (2014-11-22)
The aim of this study was to investigate the potential of using phase-contrast radiography to detect early changes in articular cartilage in a mouse model of osteoarthritis. An iodoacetate-induced mouse model of osteoarthritis was used. Mice with iodoacetate-induced osteoarthritis were
K Nakyinsige et al.
Meat science, 98(4), 701-708 (2014-08-05)
This study assessed the effect of gas stunning which has not been conducted until now in comparison with slaughter without stunning on the welfare and meat quality of rabbits. Eighty male New Zealand White rabbits were divided into two groups
Hyunji Lee et al.
Bioscience, biotechnology, and biochemistry, 78(10), 1703-1709 (2014-10-03)
Deer bone extract has the potential to relieve the discomfort or the articular cartilaginous damage associated with osteoarthritic (OA) and may be useful as a natural supplement for OA treatment without serious side effects. We analyzed the expression of pro-inflammatory
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