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PLA0207

Sigma-Aldrich

Rabbit anti-ESCO2 Antibody, Affinity Purified

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Synonym(s):

2410004I17Rik, ECO1 homolog 2, EFO2, Establishment of cohesion 1 homolog 2, RBS, Roberts syndrome, establishment of cohesion 1 homolog 2 (S. cerevisiae)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

technique(s)

immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_001017420.1

UniProt accession no.

Q56NI9

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

rabbit ... ESCO2(157570)

Immunogen

The epitope recognized by PLA0207 maps to a region between residue 200 and 250 of human establishment of cohesion 1 homolog 2 using the numbering given in entry NP_001017420.1 (GeneID 157570).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

ESCO2 (establishment of cohesion 1 homolog2) is an acetyltransferase that is essential to sister chromatid cohesion during S phase. Recent studies reveal that ESCO2 associates with components of the CoREST transcriptional repression complex. ESCO2 has also been shown to possess histone H3 K9 methylation activity. These findings suggest a role for ESCO2 in transcriptional regulation via the modulation of chromatin structure.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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