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SAB1408884

Sigma-Aldrich

Anti-ADORA2A antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(s):

ADORA2, RDC8, hA2aR

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 45.43 kDa

species reactivity

human

technique(s)

flow cytometry: suitable
western blot: 1 μg/mL

NCBI accession no.

CF147807

UniProt accession no.

P29274

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ADORA2A(135)

Related Categories

Immunogen

ADORA2A (AAH13780.1, 1 a.a. ~ 412 a.a) full-length human protein.

Sequence
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS

Physical form

Solution in phosphate buffered saline, pH 7.4

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier.
Kim DG and Bynoe MS
The Journal of Clinical Investigation, 126, 1717-1717 (2016)
Adenosine A1 and A2A Receptors in the Brain: Current Research and Their Role in Neurodegeneration.
Stockwell J
Molecules (Basel), 22, E676-E676 (2017)
Adenosine A2A receptor gene (ADORA2A) variants may increase autistic symptoms and anxiety in autism spectrum disorder.
Freitag CM
European Child & Adolescent Psychiatry, 19, 67-67 (2010)
Miriam S Giambelluca et al.
Journal of leukocyte biology, 102(3), 829-836 (2017-02-10)
Activation of the adenosine 2A receptor (A2AR) elevates intracellular levels of cAMP and acts as a physiologic inhibitor of inflammatory neutrophil functions. In this study, we looked into the impact of A2AR engagement on early phosphorylation events. Neutrophils were stimulated

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